CRISPR Cas9 Genome editing market worth $5.3 billion by 2025
The report CRISPR Cas9 Genome editing market and Patent Landscape Report , by Applications (academic research tools, drug development, agriculture, human clinical therapeutics, and animal and disease model), by Products (editing tools, cell lines, animal models and plant breeding products), by Technology (drug compound and target screening, and agriculture and industrial use), by Patent Activities (patent categories and classification, leading patent players, technical analysis of patent landscape, patent licensing and litigation) – Global Forecast, 2025.
The global markets for CRISPR-Cas9 genome editing were estimated at $1.22 billion in 2017 and it is expected to reach $5.3 billion by 2025 growing at a CAGR of 20.19 percent.
This report focuses on the CRISPR-Cas9 genome editing tools including its technology, market, and patent landscape. The report forecasts the sizes and trends of the global market as well as its sub-segments for the period 2018 to 2025. The report focuses on critical market segments to identify the key market and technology trends. Market driving factors and constraints have been considered to estimate global CRISPR-Cas9 market potential.
Patent trends have been presented in detail to understand the research and development activities happening around the world over the years. The study also delves into licensing and litigation battles which are restricting the commercial growth of the market. The report will also present a competitive landscape focusing on active players in the industry, growth strategies, strategic imperatives and detailed profiling of critical companies.
Global CRISPR-Cas9 mediated drug discovery and development market to contribute $2,403 million by 2025.
In 2017, the global CRISPR-Cas9 mediated drug discovery and development market was estimated at $435 million. The market is expected to jump to $1,305 million by 2020 and further grow by a CAGR of 23.8 per cent over a period of eight years from 2017 to contribute $2,403 million by 2025. Drug discovery application segment held 35.6 per cent of CRISPR-Cas9 market share in 2017 which is expected to increase steadily over the forecasted period and comprise 45.2 per cent of the total market share in 2025.
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USFDA announcement of CRISPR-Cas9 edited crops being treated as Non-GMOs.
The application segment is expected to grow by four times of its market size of $156 million in 2017 to $609 million in 2025. CRISPR-Cas9 tools will play a multifarious role in agriculture by enabling the industry in editing crops to make them more nutritious, enhanced taste, disease resistant, and less susceptible to drought. Agriculture and plant breeding application segment is restricted in growth by several potential regulatory requirements and ethical apprehensions.
CRISPR Cas9 Genome editing market – Top leading Players and the geographic regions
The three leading players in the CRISPR field are Intellia Therapeutics, CRISPR Therapeutics, and Editas Medicine established by CRISPR pioneers has achieved billion-dollar market capitalization and are focused on the clinical as well as non-clinical applications of CRISPR-Cas9 technology. Large biotech companies and pharmaceuticals like Novartis, Vertex, Bayer AG have skin in the CRISPR game exploring novel techniques to evolve their drug discovery and development processes, and forming strategic alliances with crucial CRISPR technology companies to devise gene-based therapies for various genetic diseases.
The North American market has the maximum number of companies dealing with CRISPR-Cas9 products or services. About 64 per cent of the top companies with business related to CRISPR-Cas9 gene editing are in the U.S or Canada. The U.S. market is leading in the field regarding the number of companies involved in genome editing.
Novel treatments for single-gene disorders such as cystic fibrosis, haemophilia and sickle cell disease are being researched using Cas9 tools.
This technique is anticipated to be useful in the prevention and cure of complex conditions, such as cancer, heart disease, mental illness, and human immunodeficiency virus (HIV) infection. Research and Development investment in the technology is growing by leaps and bounds, the technology’s potential has been explored in newer areas of animal and disease model development, drug compound and target screening, and agriculture and nutritional health products.
Clinical therapy segment is the leading focus area of R&D with 482 patent applications
The Clinical therapy market is expected to contribute significantly to the overall CRISPR-Cas9 tools market. In 2017, the global CRISPR-Cas9 mediated clinical therapy market was estimated at $185 million. The market is expected to further grow by a CAGR of 19 per cent over a period of eight years from 2017 to contribute $744 million by 2025.Clinical therapy in APAC is expected to grow at a CAGR of 19.55 per cent for the period 2017 to 2025.
Region wise APAC is almost at par with North America in innovation activities with almost 44 percent of the fillings
The North American market lead the industry in 2017 with $504 million followed by Europe at $340 million and APAC closely behind at $325 million. The Chinese government is heavily committed to CRISPR research and has awarded more than 23 million yuan ($3.5 million) to 42 CRISPR projects. With an eight-year CAGR of 19.77 per cent, the North America market is predicted to continue dominating the global markets by 2025. APAC market is presumed to assume second position in the global markets with 3.96 per cent higher market share that European market in 2025. Rapid growth in the Rest of World (RoW) market is also expected.
A complex licensing model has sprouted around the pioneering IP portfolio.
All the CRISPR patent holders and institutes associated with them have set up companies to commercialize the patents by sublicensing them for therapeutic, agriculture and many other application areas to biotech firms, pharmaceuticals, agri-businesses etc. Caribou Biosciences, ERS Genomics, Editas Medicine, Intellia Therapeutics, and CRISPR Therapeutics are the spin offs associated with CRSIPR landscape. Not many large scale commercial assignees have actively participated in the early phases of the CRISPR–Cas patent landscape. The only large establishments making it to the top ten are Dow AgroSciences and DuPont Nutrition Science (now merged as DowDuPont), together holding 20 inventions in CRISPR-Cas9 applications in agriculture and animal biotechnology.
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